SCHEMBL21160722

SCHEMBL21160722

OC(O)c1cccc(S)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGK1 P00558 3/20 0.37
PGK2 P07205 3/20 0.37
ADRB1 P08588 2/20 0.32
ADRA1A P35348 2/20 0.32
CPN1 P15169 1/20 0.32
CPB2 Q96IY4 1/20 0.32
MIF P14174 1/20 0.32
HTR2A P28223 1/20 0.32
HTR2B P41595 1/20 0.32
LMNA P02545 3/20 0.31
MAPK1 P28482 1/20 0.31
TSHR P16473 2/20 0.31
IDO1 P14902 1/20 0.31
ADRB2 P07550 1/20 0.31
HTR1A P08908 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRB3 P13945 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13934964 0.81 KMT2A (0.47) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL13626474 0.79 ADRA1A (0.46) ADRB1ADRA1AMIFHTR2AHTR2B
SCHEMBL10187499 0.76 AOC3 (0.33) PGK1PGK2ADRB1ADRA1AMIF
SCHEMBL20583946 0.76 LMNA (0.57) ADRB1ADRA1ALMNATSHRADRB2
SCHEMBL21380592 0.75 TSHR (0.36) PGK1PGK2TSHRIDO1
SCHEMBL20902925 0.75 PGK1 (0.31) PGK1PGK2IDO1
SCHEMBL458729 0.75 HDAC4 (0.47) LMNATSHRHIF1A
SCHEMBL9220399 0.75 NOTUM (0.36) PGK1PGK2IDO1
SCHEMBL21380595 0.73 SLC6A2 (0.44) HTR2ATSHRSLC6A3
SCHEMBL18394571 0.73 SLC6A2 (0.44) HTR2ATSHRSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019135136-A1 COORDINATION COMPLEXES HAVING MICROBIAL ACTIVITY AND INCORPORABLE IN HYALURONIC ACID COMPOSITIONS LAB SRL (IT) 2019-07-11 WO disclosed