Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21160726 | 0.90 | ALDH1A1 (0.59) | RAB9AALDH1A1SYKMAPK1HSD17B10 | |
| SCHEMBL20910144 | 0.80 | SYK (0.55) | RAB9AALDH1A1SYKMAPK1HSD17B10 | |
| SCHEMBL11163446 | 0.79 | ALDH1A1 (0.69) | RAB9AALDH1A1SYKMAPK1HSD17B10 | |
| SCHEMBL25827993 | 0.77 | ALDH1A1 (0.57) | RAB9AALDH1A1SYKMAPK1SMN1; SMN2 | |
| SCHEMBL2908655 | 0.75 | RAB9A (0.56) | RAB9AALDH1A1MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL25411154 | 0.74 | ALDH1A1 (0.43) | RAB9AALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL30513002 | 0.74 | ALDH1A1 (0.43) | RAB9AALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL23967195 | 0.74 | ALDH1A1 (0.59) | RAB9AALDH1A1SYKMAPK1HSD17B10 | |
| SCHEMBL7024255 | 0.74 | ALDH1A1 (0.55) | RAB9AALDH1A1MAPK1HSD17B10SMN1; SMN2 | |
| SCHEMBL31679507 | 0.74 | ALDH1A1 (0.53) | RAB9AALDH1A1SYKHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019134539-A1 | DIHYDROPYRAZOLONE AND PYRIMIDINE COMPOUND, PREPARATION METHOD AND USE THEREFOR | 四川科伦博泰生物医药股份有限公司 | 2019-07-11 | — | — | WO | disclosed |