Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9932220 | 0.72 | POLB (0.47) | SMN1; SMN2LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL13689124 | 0.71 | FFAR2 (0.57) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL11174264 | 0.71 | FFAR2 (0.57) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| Hydrochloric Acid SCHEMBL11280779 | 0.70 | FFAR2 (0.52) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| Hydrochloric Acid SCHEMBL11189725 | 0.70 | FFAR2 (0.52) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| Bromide SCHEMBL11193140 | 0.70 | FFAR2 (0.56) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL2116133 | 0.69 | FFAR2 (0.49) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL11172873 | 0.68 | LMNA (0.50) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL11188552 | 0.68 | LMNA (0.50) | FFAR2SMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL10995217 | 0.67 | TSHR (0.41) | ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095003-A1 | METHODS OF USING PRODRUGS OF METHYL HYDROGEN FUMARATE AND PHARMACEUTICAL COMPOSITIONS THEREOF | XENOPORT, INC. (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095003-A1 | METHODS OF USING PRODRUGS OF METHYL HYDROGEN FUMARATE AND PHARMACEUTICAL COMPOSITIONS THEREOF | FH, MGMT, BHMT2 | FFAR2 162/4885SMN1; SMN2 2337/4885RAB9A 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.