SCHEMBL21161559

SCHEMBL21161559

c1ccc2c(-c3cccc4c3sc3ccccc34)nc(-n3c4ccccc4c4cc(-n5c6ccccc6c6ccccc65)ccc43)nc2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.36
PRKDC P78527 6/20 0.32
KDM4E B2RXH2 4/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ATM Q13315 1/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
PARP14 Q460N5 1/20 0.32
HPGD P15428 2/20 0.31
NPC1 O15118 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 2/20 0.31
ALDH1A1 P00352 2/20 0.31
NPSR1 Q6W5P4 1/20 0.31
BRD4 O60885 1/20 0.31
PIK3CA P42336 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24030261 0.92 ALOX5 (0.32) ALOX5
SCHEMBL21716322 0.91 ALOX5 (0.33) ALOX5PRKDCHPGD
SCHEMBL15583017 0.91 ALOX5 (0.38) ALOX5PRKDCKDM4EL3MBTL1ATM
SCHEMBL21716574 0.90 HPGD (0.32) ALOX5HPGD
SCHEMBL23471996 0.89
SCHEMBL22893867 0.89 ALOX5 (0.40) ALOX5PRKDCKDM4EL3MBTL1ATM
SCHEMBL21213733 0.88 ALOX5 (0.36) ALOX5PRKDCKDM4EL3MBTL1PIK3CD
SCHEMBL24030473 0.88 ALOX5 (0.31) ALOX5PRKDC
SCHEMBL19653951 0.88 KDM4E (0.35) ALOX5PRKDCKDM4EL3MBTL1ATM
SCHEMBL15589069 0.87 ALOX5 (0.38) ALOX5PRKDCKDM4EL3MBTL1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220216433-A1 ELECTROLUMINESCENT DEVICE Beijing Summer Sprout Technology Co., Ltd. (CN) 2022-07-07 US disclosed
US-10971687-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-06 US disclosed
US-20190189930-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220216433-A1 ELECTROLUMINESCENT DEVICE EML4, EMC2, L1CAM ALOX5 4395/4885PRKDC 3716/4885KDM4E 1502/4885
US-10971687-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, XDH ALOX5 737/4885PRKDC 4085/4885KDM4E 1163/4885
US-20190189930-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, XDH ALOX5 737/4885PRKDC 4085/4885KDM4E 1163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.