SCHEMBL21164655

SCHEMBL21164655

C=CCNCC(=O)NC(C)(CC)CCCC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.40
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 1/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.32
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
TRPV1 Q8NER1 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10045201 0.76 ALDH1A1 (0.41) FAAHALDH1A1KDM4ESMN1; SMN2MAPT
SCHEMBL21164656 0.76 KDM4E (0.41) FAAHALDH1A1KDM4EGAATSHR
SCHEMBL18948819 0.75 EPHX1 (0.42) FAAHALDH1A1TSHRMAPTTRPV1
SCHEMBL8764497 0.74 ZDHHC20 (0.44) FAAHALDH1A1GAAHPGDTSHR
SCHEMBL18867143 0.73 ADH1B (0.39) ALDH1A1GAATSHRCNR1HRH3
SCHEMBL23682848 0.71 ALDH1A1 (0.42) ALDH1A1HRH3
SCHEMBL19069143 0.71 ALDH1A1 (0.39) ALDH1A1TSHRHRH3
SCHEMBL18948738 0.70 ADH1B (0.43) FAAHALDH1A1TSHRMAPTTRPV1
SCHEMBL11410139 0.69 ALDH1A1 (0.37) ALDH1A1MAPT
SCHEMBL18867159 0.68 ADH1B (0.44) FAAHALDH1A1TSHRMAPTTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351883-B2 Compounds for increasing lipid synthesis and storage NUTECH VENTURES (US) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351883-B2 Compounds for increasing lipid synthesis and storage FASN, LIPC, SREBF2 FAAH 561/4885ALDH1A1 1121/4885KDM4E 1755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.