Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136357 | 0.79 | CTSK (0.62) | CYP1A2CTSKCTSSCTSLCTSB | |
| SCHEMBL12294550 | 0.79 | CYP2D6 (0.62) | CYP1A2CAPN1CAPN2CTSKTPSAB1 | |
| SCHEMBL18681571 | 0.78 | CTSL (0.53) | CYP1A2CAPN1CTSKCTSSCTSL | |
| SCHEMBL20542840 | 0.77 | SIRT2 (0.60) | SIRT2SIRT1SIRT3 | |
| SCHEMBL20542838 | 0.77 | SIRT2 (0.60) | SIRT2SIRT1SIRT3 | |
| SCHEMBL10481494 | 0.77 | SIRT2 (0.60) | SIRT2SIRT1SIRT3 | |
| SCHEMBL10035698 | 0.77 | CYP1A2 (0.57) | CYP1A2CAPN1CAPN2CTSKCTSS | |
| SCHEMBL15318479 | 0.76 | CA5A (0.62) | CYP1A2CTSKCTSSCTSLCTSB | |
| SCHEMBL8502694 | 0.76 | CYP1A2 (0.58) | CYP1A2CTSKCTSSCTSLCTSB | |
| SCHEMBL10957418 | 0.76 | CYP1A2 (0.58) | CYP1A2CAPN1CAPN2CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10351595-B2 | — | — | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351595-B2 | — | MRPL21, PRSS1, PEPD | CYP1A2 4529/4885GAA 526/4885CAPN1 122/4885 |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | MRPL21, PEPD, CTSC | CYP1A2 4095/4885GAA 978/4885CAPN1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.