Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | IGLV6-57 | P01721 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165084 | 0.76 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL28379902 | 0.74 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL21164867 | 0.72 | ERN1 (0.50) | ALDH1A1MAPTKDM4EHPGDHSD17B10 | |
| SCHEMBL2845185 | 0.72 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL8124438 | 0.70 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL5462848 | 0.70 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL31268246 | 0.70 | ALDH1A1 (0.57) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL7678827 | 0.70 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL11041194 | 0.70 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL2845181 | 0.68 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | IK, CYBA, CRY2 | ALDH1A1 192/4885L3MBTL1 2326/4885MAPT 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.