Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.34 |
| ▸ | MEN1 | O00255 | 10/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 7/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21165239 | 0.86 | — | — | |
| SCHEMBL21165162 | 0.79 | NFE2L2 (0.43) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL21165152 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL21165163 | 0.68 | NFE2L2 (0.33) | ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL1416417 | 0.62 | S100B (0.45) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL1416418 | 0.62 | S100B (0.45) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL9342036 | 0.61 | ACHE (0.49) | ALDH1A1MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL9632481 | 0.61 | S100B (0.43) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL11319345 | 0.61 | ACHE (0.49) | ALDH1A1MEN1KMT2ACRHBPCRHR2 | |
| SCHEMBL11041194 | 0.60 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351706-B2 | Near-infrared fluorescent dyes and uses thereof | IK, CYBA, CRY2 | ALDH1A1 192/4885MEN1 1633/4885KMT2A 3888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.