SCHEMBL21165314

SCHEMBL21165314

CCNc1ccc(C(c2ccc(Nc3ccccc3)cc2)c2ccc(Nc3ccccc3)cc2)c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 7/20 0.49
MAPT P10636 4/20 0.38
TDP1 Q9NUW8 3/20 0.38
KMT2A Q03164 3/20 0.38
RECQL P46063 2/20 0.38
MEN1 O00255 2/20 0.38
GAA P10253 2/20 0.38
KDM4E B2RXH2 2/20 0.38
GLA P06280 1/20 0.38
ALDH1A1 P00352 4/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 4/20 0.36
ALOX15 P16050 3/20 0.36
TSHR P16473 3/20 0.36
ALOX12 P18054 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
MAPK1 P28482 2/20 0.36
PTGS1 P23219 1/20 0.36
SLC6A2 P23975 1/20 0.36
PTGS2 P35354 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009559 0.81 IDO1 (0.45) IDO1MAPTTDP1KMT2AMEN1
Hydrochloric Acid SCHEMBL14895281 0.80 IDO1 (0.44) IDO1MAPTTDP1KMT2AMEN1
SCHEMBL110473 0.80 IDO1 (0.44) IDO1KMT2AMEN1ALDH1A1TSHR
Hydrochloric Acid SCHEMBL11238001 0.78 IDO1 (0.43) IDO1KMT2AMEN1ALDH1A1TSHR
SCHEMBL21165374 0.78 HPGD (0.46) MAPTTDP1KMT2ARECQLMEN1
SCHEMBL3901015 0.77 KDM1A (0.47) MAPTTDP1KMT2ARECQLMEN1
SCHEMBL21165197 0.76 RAPGEF4 (0.42) MAPTTDP1KMT2ARECQLMEN1
SCHEMBL23054293 0.76 CNR2 (0.42) IDO1MAPTTDP1GAAKDM4E
SCHEMBL111466 0.75 MEN1 (0.45) MAPTTDP1KMT2ARECQLMEN1
SCHEMBL21165196 0.75 CDC25B (0.60) MAPTTDP1KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 IDO1 3157/4885MAPT 1958/4885TDP1 3830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.