SCHEMBL21165196

SCHEMBL21165196

CCOC(=O)c1ccccc1Nc1ccc(C(c2ccc(Nc3ccccc3)cc2)c2ccc(Nc3ccccc3)cc2)c2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 10/20 0.60
CDC25A P30304 1/20 0.57
CDC25C P30307 1/20 0.57
ALDH1A1 P00352 4/20 0.47
MAPT P10636 3/20 0.47
KDM4E B2RXH2 3/20 0.47
KMT2A Q03164 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
NPY1R P25929 1/20 0.44
NPY2R P49146 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
GPR55 Q9Y2T6 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 3/20 0.44
HSD17B10 Q99714 2/20 0.44
METTL3 Q86U44 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21165313 0.92 CDC25B (0.58) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL21165037 0.88 CDC25B (0.54) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL18351144 0.86 CDC25B (0.57) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL21165365 0.85 CDC25B (0.50) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL2008034 0.78 MAPT (0.71) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL21165314 0.75 IDO1 (0.49) ALDH1A1MAPTKDM4EKMT2ATDP1
SCHEMBL18351202 0.73 CDC25B (1.00) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL21165374 0.73 HPGD (0.46) CDC25BCDC25AALDH1A1MAPTKDM4E
SCHEMBL10833818 0.72 CDC25B (0.65) CDC25BCDC25ACDC25CALDH1A1MAPT
SCHEMBL4544856 0.71 CDC25B (0.60) CDC25BCDC25ACDC25CALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation FUJIFILM CORPORATION (JP) 2019-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10351526-B2 Coloring curable resin composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, compound, and cation O60361, WDR12, SEM1 CDC25B 4620/4885CDC25A 4564/4885CDC25C 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.