SCHEMBL2116544

SCHEMBL2116544

CCC(C)(O)C#Cc1[c]cccc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
CCNB2 O95067 2/20 0.33
CDK1 P06493 2/20 0.33
CCNB1 P14635 2/20 0.33
CDK5 Q00535 2/20 0.33
CCNB3 Q8WWL7 2/20 0.33
PGK1 P00558 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2116025 0.85
SCHEMBL2113845 0.82 L3MBTL1 (0.34) MAPT
SCHEMBL11048323 0.73 MAPT (0.64) MAPTCCNB2CDK1CCNB1CDK5
SCHEMBL483300 0.71 KDM4E (0.34)
SCHEMBL2118609 0.70 MAPT (0.44) MAPTCCNB2CDK1CCNB1CDK5
SCHEMBL2116984 0.69 MAPT (0.43) MAPTCCNB2CDK1CCNB1CDK5
SCHEMBL2649459 0.69 ALDH1A1 (0.36)
SCHEMBL613219 0.68 KCNH2 (0.39)
SCHEMBL483062 0.68
SCHEMBL613452 0.66 KCNH2 (0.47) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2555053-B1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2017-10-18 EP disclosed
EP-2555053-A1 Positive-type photosensitive resin composition Toray Industries, Inc. (JP) 2013-02-06 EP disclosed
EP-2110708-B1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES (JP) 2012-12-05 EP disclosed
US-8158324-B2 Positive-type photosensitive resin composition TORAY INDUSTRIES, INC. (JP) 2012-04-17 US disclosed
US-20100099041-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-04-22 US disclosed
EP-2110708-A1 POSITIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION Toray Industries, Inc. (JP) 2009-10-21 EP disclosed