SCHEMBL211668

SCHEMBL211668

CC(C)[SiH](ON=Cc1ccccn1)C(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.46
MAOA P21397 2/20 0.45
MEN1 O00255 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KMT2A Q03164 2/20 0.42
ATM Q13315 1/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
USP2 O75604 1/20 0.41
MAOB P27338 1/20 0.41
TOP2A P11388 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CTH P32929 1/20 0.39
G6PC1 P35575 1/20 0.39
SLC2A1 P11166 1/20 0.39
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215884 0.81 NR4A1 (0.50) NR4A1MAOAMEN1NPC1RAB9A
SCHEMBL215886 0.77 CTH (0.39) RAB9AKMT2ACTH
SCHEMBL213146 0.75 NR4A1 (0.55) NR4A1MAOAMEN1NPC1RAB9A
SCHEMBL213145 0.75 NR4A1 (0.55) NR4A1MAOAMEN1NPC1RAB9A
Hydrochloric Acid SCHEMBL6166208 0.74 NR4A1 (0.53) NR4A1MAOAMEN1NPC1RAB9A
SCHEMBL212402 0.74 LMNA (0.41) MEN1NPC1RAB9AKMT2ALMNA
Hydrochloric Acid SCHEMBL6166204 0.74 NR4A1 (0.53) NR4A1MAOAMEN1NPC1RAB9A
SCHEMBL215449 0.73 NR4A1 (0.52) NR4A1MAOAMEN1NPC1RAB9A
SCHEMBL215448 0.73 NR4A1 (0.52) NR4A1MAOAMEN1NPC1RAB9A
SCHEMBL878896 0.72 NR4A1 (0.55) NR4A1MAOAMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US claimed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US claimed
US-8088868-B2 oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis BRIDGESTONE CORPORATION (JP) 2012-01-03 US disclosed
US-20080146745-A1 POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS BRIDGESTONE CORPORATION (JP) 2008-06-19 US disclosed