Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214192 | 0.79 | PLA2G7 (0.46) | LMNAL3MBTL1PLA2G7NPC1RAB9A | |
| SCHEMBL212648 | 0.78 | LMNA (0.46) | LMNAL3MBTL1PLA2G7MIFNPC1 | |
| SCHEMBL212225 | 0.75 | ALDH1A1 (0.53) | LMNAL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL211929 | 0.74 | GRIN2D (0.46) | LMNARAB9ASMN1; SMN2GAAMEN1 | |
| SCHEMBL211668 | 0.74 | NR4A1 (0.46) | LMNAL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5410827 | 0.74 | PPARG (0.49) | LMNAL3MBTL1PLA2G7MIFNPC1 | |
| SCHEMBL13318830 | 0.74 | PPARG (0.49) | LMNAL3MBTL1PLA2G7MIFNPC1 | |
| SCHEMBL213216 | 0.72 | SMN1; SMN2 (0.48) | LMNAL3MBTL1PLA2G7NPC1RAB9A | |
| SCHEMBL113601 | 0.70 | LMNA (0.52) | LMNAL3MBTL1PLA2G7MIFNPC1 | |
| SCHEMBL10797604 | 0.70 | LMNA (0.52) | LMNAL3MBTL1PLA2G7MIFNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |