SCHEMBL21166968

SCHEMBL21166968

CC(=O)N1CCCC1C(=O)NC(CCC(=O)O)C(=O)NCCCOCCOCCOCCCN

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 8/20 0.41
ITGA2B P08514 8/20 0.41
ITGB1 P05556 2/20 0.41
ITGA4 P13612 2/20 0.41
F2 P00734 3/20 0.40
APLNR P35414 1/20 0.40
REN P00797 1/20 0.39
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
CHRNA1 P02708 1/20 0.38
CHRNG P07510 1/20 0.38
CHRNB1 P11230 1/20 0.38
CHRND Q07001 1/20 0.38
NTMT1 Q9BV86 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21350917 0.92 APLNR (0.40) ITGB3ITGA2BITGB1ITGA4F2
SCHEMBL19681264 0.90 POLB (0.44) ITGB3ITGA2BF2APLNRPOLB
SCHEMBL21166989 0.88 ACE (0.45) ITGB3ITGA2BITGB1ITGA4F2
SCHEMBL21166966 0.86 ITGB1 (0.44) ITGB3ITGA2BITGB1ITGA4F2
SCHEMBL21167115 0.86 ITGB1 (0.44) ITGB3ITGA2BITGB1ITGA4F2
SCHEMBL21167022 0.86 APLNR (0.46) ITGB3ITGA2BITGB1ITGA4F2
SCHEMBL21339699 0.85 ITGB1 (0.39) ITGB1ITGA4F2APLNRREN
SCHEMBL21347008 0.84 CHRNA1 (0.55) F2RENCHRNA1CHRNGCHRNB1
SCHEMBL21350916 0.83 TSHR (0.39) ITGB1ITGA4F2APLNRREN
SCHEMBL19681206 0.82 TSHR (0.54) F2POLBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210401943-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN AGONIST RECEPTOR OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID ADOCIA (FR) 2021-12-30 US disclosed
US-20210386830-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID ADOCIA (FR) 2021-12-16 US disclosed
US-11191812-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid ADOCIA (FR) 2021-12-07 US disclosed
US-11129877-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin agonist receptor or an amylin analogue and a co-polyamino acid ADOCIA (FR) 2021-09-28 US disclosed
US-20200306379-A1 INJECTABLE PH 7 SOLUTION COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI FROM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS ADOCIA (FR) 2020-10-01 US disclosed
US-20190328842-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN AGONIST RECEPTOR OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID ADOCIA (FR) 2019-10-31 US disclosed
US-20190275109-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID ADOCIA (FR) 2019-09-12 US disclosed
US-20190216931-A1 INJECTABLE PH 7 SOLUTION COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI FROM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS ADOCIA (FR) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11191812-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid GCG, GIPR, GLP1R ITGB3 3010/4885ITGA2B 4164/4885ITGB1 4576/4885
US-20190275109-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID GCG, GIPR, GLP1R ITGB3 2874/4885ITGA2B 3903/4885ITGB1 4540/4885
US-11129877-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin agonist receptor or an amylin analogue and a co-polyamino acid IAPP, GLP1R, INSR ITGB3 2934/4885ITGA2B 2686/4885ITGB1 3600/4885
US-20200306379-A1 INJECTABLE PH 7 SOLUTION COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI FROM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS IAPP, INSR, IGFBP5 ITGB3 2335/4885ITGA2B 3365/4885ITGB1 3057/4885
US-20190216931-A1 INJECTABLE PH 7 SOLUTION COMPRISING AT LEAST ONE BASAL INSULIN HAVING A PI FROM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS IAPP, INSR, IGFBP5 ITGB3 2335/4885ITGA2B 3365/4885ITGB1 3057/4885
US-20190328842-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN AGONIST RECEPTOR OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID IAPP, GLP1R, INSR ITGB3 2934/4885ITGA2B 2686/4885ITGB1 3600/4885
US-20210386830-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING HUMAN GLUCAGON AND A CO-POLYAMINO ACID GCG, GIPR, GLP1R ITGB3 3010/4885ITGA2B 4164/4885ITGB1 4576/4885
US-20210401943-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN AGONIST RECEPTOR OR AN AMYLIN ANALOGUE AND A CO-POLYAMINO ACID IAPP, GLP1R, INSR ITGB3 2934/4885ITGA2B 2686/4885ITGB1 3600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.