SCHEMBL21339699

SCHEMBL21339699

COC(=O)CCC(NC(=O)C1CCCN1C(C)=O)C(=O)NCCCOCCOCCOCCCNC(=O)CCC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB1 P05556 2/20 0.39
ITGA4 P13612 2/20 0.39
GLP1R P43220 8/20 0.38
POLB P06746 1/20 0.37
TSHR P16473 1/20 0.37
TNKS O95271 2/20 0.36
F2 P00734 1/20 0.36
PRCP P42785 1/20 0.35
REN P00797 1/20 0.35
CCKAR P32238 1/20 0.35
CCKBR P32239 1/20 0.35
APLNR P35414 1/20 0.35
MMP1 P03956 1/20 0.34
MMP3 P08254 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21350916 0.89 TSHR (0.39) ITGB1ITGA4POLBTSHRF2
SCHEMBL21350917 0.88 APLNR (0.40) ITGB1ITGA4POLBTSHRF2
SCHEMBL21339798 0.88 MMP3 (0.43) ITGB1ITGA4POLBTSHRREN
SCHEMBL21166968 0.85 ITGB3 (0.41) ITGB1ITGA4POLBTSHRF2
SCHEMBL21339696 0.84 TSHR (0.50) ITGB1ITGA4POLBTSHRTNKS
SCHEMBL21339761 0.84 REN (0.48) ITGB1ITGA4TNKSPRCPREN
SCHEMBL21350915 0.83 ITGB1 (0.42) ITGB1ITGA4TNKSF2APLNR
SCHEMBL21350914 0.81 ITGB1 (0.42) ITGB1ITGA4F2RENAPLNR
SCHEMBL21339704 0.79 MMP3 (0.40) POLBTSHRTNKSRENAPLNR
SCHEMBL19681264 0.77 POLB (0.44) POLBTSHRF2APLNRMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals ADOCIA (FR) 2023-04-25 US disclosed
US-20220409523-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG AND A CO-POLYAMINO ACID ADOCIA (FR) 2022-12-29 US disclosed
US-11173109-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid ADOCIA (FR) 2021-11-16 US disclosed
US-10987426-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid ADOCIA (FR) 2021-04-27 US disclosed
US-20190274954-A1 Copositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid ADOCIA (FR) 2019-09-12 US disclosed
US-20190275115-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS ADOCIA (FR) 2019-09-12 US disclosed
US-20190275156-A1 COMPOSITIONS SOUS FORME D'UNE SOLUTION AQUEUSE INJECTABLE COMPRENANT DU GLUCAGON HUMAIN ET UN CO-POLYAMINOACIDE ADOCIA (FR) 2019-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals IAPP, HBB, IGF1R ITGB1 1825/4885ITGA4 3642/4885GLP1R 11/4885
US-20190275156-A1 COMPOSITIONS SOUS FORME D'UNE SOLUTION AQUEUSE INJECTABLE COMPRENANT DU GLUCAGON HUMAIN ET UN CO-POLYAMINOACIDE GCG, GLP1R, GHSR ITGB1 4817/4885ITGA4 4842/4885GLP1R 2/4885
US-20190274954-A1 Copositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid IAPP, GLP1R, INSR ITGB1 3532/4885ITGA4 3047/4885GLP1R 2/4885
US-20220409523-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG AND A CO-POLYAMINO ACID IAPP, INSR, GLP1R ITGB1 3146/4885ITGA4 2658/4885GLP1R 3/4885
US-10987426-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid GCG, GLP1R, GCGR ITGB1 4428/4885ITGA4 4392/4885GLP1R 2/4885
US-11173109-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid IAPP, INSR, GLP1R ITGB1 3329/4885ITGA4 2820/4885GLP1R 3/4885
US-20190275115-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS IAPP, GCG, HBB ITGB1 2241/4885ITGA4 3570/4885GLP1R 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.