Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20987492 | 0.92 | APP (0.46) | APPERN1CA1CA9CA2 | |
| SCHEMBL21167122 | 0.83 | APP (0.39) | APPERN1CA1CA9CA2 | |
| SCHEMBL20987497 | 0.77 | RORA (0.41) | APPERN1CA1CA9CA2 | |
| SCHEMBL21023296 | 0.77 | PRKDC (0.43) | APPCA1CA9CA2NPC1 | |
| SCHEMBL14302581 | 0.76 | APP (0.54) | APPERN1CA1CA9CA2 | |
| SCHEMBL21167110 | 0.75 | MAOB (0.57) | NPC1RAB9AL3MBTL1ATMPOLB | |
| SCHEMBL21166974 | 0.73 | ALOX5 (0.52) | NPC1RAB9AL3MBTL1ATMPOLB | |
| SCHEMBL13129267 | 0.72 | APP (0.61) | APPERN1CA1CA9CA2 | |
| SCHEMBL21166970 | 0.72 | L3MBTL1 (0.63) | NPC1RAB9AL3MBTL1ATMPOLB | |
| SCHEMBL32677328 | 0.71 | APP (0.81) | APPERN1CA1CA9CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190221745-A1 | PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND | FUJIFILM CORPORATION (JP) | 2019-07-18 | — | — | US | disclosed |