SCHEMBL21167121

SCHEMBL21167121

Cn1c2cc3c(=O)c4c(-c5ccc6cc7ccccc7cc6c5)cc(-c5ccc6cc7ccccc7cc6c5)cc4n(C)c3cc2c(=O)c2c(-c3ccc4cc5ccccc5cc4c3)cc(-c3ccc4cc5ccccc5cc4c3)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.40
GSTP1 P09211 1/20 0.40
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
LMNA P02545 1/20 0.35
MAOB P27338 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HTR1D P28221 1/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
ATM Q13315 1/20 0.33
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21167123 0.96 GSTP1 (0.44) L3MBTL1GSTP1NPC1RAB9APOLB
SCHEMBL21167124 0.81 HSD17B10 (0.45) L3MBTL1NPC1RAB9APOLBGAA
SCHEMBL20987443 0.81 L3MBTL1 (0.45) L3MBTL1GSTP1NPC1RAB9APOLB
SCHEMBL21167128 0.76 NTRK1 (0.36) L3MBTL1GAAMAOB
SCHEMBL21167119 0.75 MAPT (0.40) L3MBTL1NPC1RAB9APOLBGAA
SCHEMBL21023334 0.75 GSTP1 (0.41) L3MBTL1GSTP1NPC1RAB9AGAA
SCHEMBL21167106 0.74 ALDH1A1 (0.40) L3MBTL1NPC1RAB9APOLBMAOB
SCHEMBL28107677 0.74 HSD17B10 (0.44) L3MBTL1NPC1RAB9AHTR1DRXRA
SCHEMBL21167130 0.72 BRD4 (0.40) L3MBTL1NPC1RAB9APOLBGAA
SCHEMBL21167125 0.71 ATM (0.40) L3MBTL1NPC1RAB9APOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190221745-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed