SCHEMBL21167124

SCHEMBL21167124

Cn1c2cc3c(=O)c4c(-c5ccccc5)cc(-c5ccccc5)cc4n(C)c3cc2c(=O)c2c(-c3ccccc3)cc(-c3ccccc3)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.45
MAOB P27338 1/20 0.43
CHEK1 O14757 1/20 0.41
WEE1 P30291 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.39
RET P07949 1/20 0.39
HPGD P15428 1/20 0.39
BRD4 O60885 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
ATM Q13315 1/20 0.38
CDC25A P30304 1/20 0.37
CDC25C P30307 1/20 0.37
CYP2C19 P33261 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
KDM1A O60341 1/20 0.36
MAPK14 Q16539 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21167128 0.85 NTRK1 (0.36) MAOBL3MBTL1RETGAAKDM4E
SCHEMBL21167106 0.83 ALDH1A1 (0.40) HSD17B10MAOBL3MBTL1HPGDBRD4
SCHEMBL21167123 0.82 GSTP1 (0.44) MAOBL3MBTL1RXRARXRBMAPT
SCHEMBL21167113 0.81 ALDH1A1 (0.44) HSD17B10HPGDCDC25ACDC25CCYP2C19
SCHEMBL21167120 0.81 CDC25A (0.49) HSD17B10CHEK1WEE1L3MBTL1BRD4
SCHEMBL21167121 0.81 L3MBTL1 (0.40) MAOBL3MBTL1BRD4RXRARXRB
SCHEMBL21167114 0.81 ATM (0.37) HSD17B10L3MBTL1MAPTHTTATM
SCHEMBL22544312 0.80 HSD17B10 (0.53) HSD17B10CHEK1WEE1L3MBTL1HPGD
SCHEMBL21167130 0.78 BRD4 (0.40) HSD17B10L3MBTL1HPGDBRD4MAPT
SCHEMBL21167110 0.78 MAOB (0.57) HSD17B10MAOBL3MBTL1HPGDBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230345826-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
US-20230345826-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230132579-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed
US-20230121151-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-04-20 US disclosed
US-20190221745-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2019-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230345826-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND TEAD1, CRY1, CPNE4 HSD17B10 4007/4885MAOB 3131/4885CHEK1 2539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.