Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24591075 | 0.90 | SYK (0.40) | SYKNPC1SSTR3METKDR | |
| SCHEMBL21167803 | 0.87 | MET (0.45) | SYKNPC1METHDAC6KDR | |
| SCHEMBL21167474 | 0.85 | SYK (0.48) | WNT3ASYKNPC1SSTR3KCNH2 | |
| SCHEMBL22475720 | 0.83 | MET (0.49) | SYKNPC1KCNH2HRH3MET | |
| SCHEMBL24591052 | 0.83 | SYK (0.46) | WNT3ASYKNPC1SSTR3KCNH2 | |
| SCHEMBL21167707 | 0.82 | MET (0.48) | SYKMETKDR | |
| SCHEMBL22475774 | 0.79 | NPC1 (0.39) | SYKNPC1SSTR3HDAC6KDR | |
| SCHEMBL24591141 | 0.79 | MET (0.54) | MET | |
| SCHEMBL22754430 | 0.79 | MET (0.44) | SYKMETHDAC6KDR | |
| SCHEMBL22476000 | 0.78 | GRM5 (0.41) | NPC1METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-B1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | HUTCHISON MEDIPHARMA LTD (CN) | 2020-09-30 | — | — | EP | disclosed |
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |