Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 6/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 3/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 6/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21167476 | 0.87 | WNT3A (0.40) | METSYKNPC1KDRHDAC6 | |
| SCHEMBL21167804 | 0.86 | MET (0.47) | METHDAC1SYKKCNA5NPC1 | |
| SCHEMBL22475874 | 0.85 | MET (0.46) | METHDAC1SYKKCNA5NPC1 | |
| SCHEMBL24591075 | 0.84 | SYK (0.40) | METSYKNPC1KDRFLT1 | |
| SCHEMBL22475720 | 0.80 | MET (0.49) | METSYKNPC1KDRFLT1 | |
| SCHEMBL21167568 | 0.78 | KDR (0.40) | METNPC1KDRHDAC6FLT1 | |
| SCHEMBL21167707 | 0.77 | MET (0.48) | METSYKKDR | |
| SCHEMBL22475774 | 0.76 | NPC1 (0.39) | SYKNPC1KDRHDAC6FLT1 | |
| SCHEMBL24591141 | 0.76 | MET (0.54) | MET | |
| SCHEMBL24591122 | 0.76 | MET (0.44) | MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3511330-A1 | SYNTHETIC INTERMEDIATE USEFUL IN THE PREPARATION OF TRIAZOLOPYRIDINE C-MET INHIBITORS | Hutchison Medipharma Limited (CN) | 2019-07-17 | — | — | EP | disclosed |