Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21168648 | 0.90 | GPR84 (0.41) | KMT2ASMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL204295 | 0.85 | ALDH1A1 (0.41) | KMT2ASMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL3936080 | 0.81 | RAB9A (0.62) | KMT2ASMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL205849 | 0.80 | MEN1 (0.40) | KMT2ASMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL13638790 | 0.77 | NPC1 (0.47) | KMT2ASMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL14186840 | 0.75 | TP53 (0.51) | GPR84TP53MAPK1TSHRCYP1A2 | |
| SCHEMBL12925858 | 0.74 | GPR84 (0.44) | KMT2AMEN1GPR84TP53MAPK1 | |
| SCHEMBL15298486 | 0.73 | PLA2G2A (0.53) | TP53MAPK1TSHR | |
| SCHEMBL8251597 | 0.72 | GPR84 (0.42) | GPR84TP53MAPK1TSHRCYP1A2 | |
| SCHEMBL17693528 | 0.72 | GPR84 (0.40) | SMN1; SMN2GPR84TP53MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331860-B1 | INDANYLAMINOPYRIDYLCYCLOPROPANECARBOXYLIC ACIDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2019-07-17 | — | — | EP | disclosed |