Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18327107 | 0.85 | CYP1A2 (0.52) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL14418508 | 0.84 | LMNA (0.52) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL11170402 | 0.81 | PGR (0.52) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL1824157 | 0.79 | PGR (0.55) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL17002137 | 0.79 | PGR (0.55) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL18862287 | 0.79 | LMNA (0.46) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL11230623 | 0.78 | PGR (0.49) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL10807467 | 0.78 | GABRR1 (0.52) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL2092216 | 0.78 | PGR (0.49) | LMNAALDH1A1PGRADRA2AADRA2B | |
| SCHEMBL24896949 | 0.77 | HDAC1 (0.53) | LMNAALDH1A1PGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11230565-B2 | Synthesis of backbone modified morpholino oligonucleotides and chimeras using phosphoramidite chemistry | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2022-01-25 | — | — | US | disclosed |
| US-20210277047-A1 | Synthesis and Biological Activity of Phosphoramidimidate and Phosphoramidate DNA | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2021-09-09 | — | — | US | disclosed |
| US-20190218236-A1 | SYNTHESIS OF BACKBONE MODIFIED MORPHOLINO OLIGONUCLEOTIDES AND CHIMERAS USING PHOSPHORAMIDITE CHEMISTRY | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11230565-B2 | Synthesis of backbone modified morpholino oligonucleotides and chimeras using phosphoramidite chemistry | RNASEH1, RNASE1, PMM2 | LMNA 809/4885ALDH1A1 4192/4885PGR 3378/4885 |
| US-20190218236-A1 | SYNTHESIS OF BACKBONE MODIFIED MORPHOLINO OLIGONUCLEOTIDES AND CHIMERAS USING PHOSPHORAMIDITE CHEMISTRY | RNASEH1, RNASE1, PMM2 | LMNA 809/4885ALDH1A1 4192/4885PGR 3378/4885 |
| US-20210277047-A1 | Synthesis and Biological Activity of Phosphoramidimidate and Phosphoramidate DNA | RNASEH1, RNASE1, DNASE1 | LMNA 995/4885ALDH1A1 3210/4885PGR 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.