Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500471 | 0.93 | CYP3A4 (0.44) | CETPLMNATSHRMAPK1HTR2A | |
| SCHEMBL23072505 | 0.92 | TAAR1 (0.46) | CETPLMNATSHRMAPK1HTR2A | |
| SCHEMBL7752962 | 0.89 | AR (0.45) | CETPTSHRMAPK1HTR2AHTR2B | |
| SCHEMBL19265466 | 0.86 | HTR7 (0.43) | CETPLMNATSHRMAPK1HTR2A | |
| SCHEMBL8626864 | 0.85 | CYP3A4 (0.55) | CETPLMNATSHRMAPK1HTR2A | |
| SCHEMBL23222205 | 0.82 | LMNA (0.39) | CETPLMNATSHRMAPK1HTR2A | |
| SCHEMBL10700469 | 0.81 | MEN1 (0.54) | CETPTSHRMAPK1CYP3A4MAPT | |
| SCHEMBL10734840 | 0.81 | CETP (0.47) | CETPTSHRMAPK1HTR2AHTR2B | |
| SCHEMBL5073885 | 0.79 | RORC (0.47) | LMNATSHRMAPK1CYP3A4TDP1 | |
| SCHEMBL4617153 | 0.78 | CETP (0.43) | CETPLMNATSHRMAPK1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661961-A | A method of inhibit tree species to generate willow catkins flying in the air or flying hair | 北京市园林科学研究院 | 2019-04-23 | — | — | CN | claimed |
| CN-109644757-A | A method of inhibiting the bud differentiation of ginkgo female plant | 北京市园林科学研究院 | 2019-04-19 | — | — | CN | claimed |
| CN-109362741-A | A method of inhibit plant to generate Allergic pollen | 北京市园林科学研究院 | 2019-02-22 | — | — | CN | claimed |
| CN-109329280-A | A kind of medicament and its application method inhibiting evergreen landscape tree species bud differentiation | 北京市园林科学研究院 | 2019-02-15 | — | — | CN | claimed |
| EP-3207929-B1 | COLCHICINE DERIVATIVES FOR THE TREATMENT OF CANCER | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2021-05-26 | — | — | EP | disclosed |
| US-10870657-B2 | Compounds for the treatment of cancer and inflammatory disease | SHY Therapeutics LLC (US) | 2020-12-22 | — | — | US | disclosed |
| US-20190218229-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMTORY DISEASE | SHY Therapeutics LLC | 2019-07-18 | — | — | US | disclosed |
| CN-109661961-A | A method of inhibit tree species to generate willow catkins flying in the air or flying hair | 北京市园林科学研究院 | 2019-04-23 | — | — | CN | disclosed |
| CN-109644757-A | A method of inhibiting the bud differentiation of ginkgo female plant | 北京市园林科学研究院 | 2019-04-19 | — | — | CN | disclosed |
| CN-109362741-A | A method of inhibit plant to generate Allergic pollen | 北京市园林科学研究院 | 2019-02-22 | — | — | CN | disclosed |
| CN-109329280-A | A kind of medicament and its application method inhibiting evergreen landscape tree species bud differentiation | 北京市园林科学研究院 | 2019-02-15 | — | — | CN | disclosed |
| CN-87104533-A | Heterogeneous ring compound | — | 1988-01-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218229-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMTORY DISEASE | MAPK1, MAPK6, MAP3K1 | CETP 2990/4885LMNA 3409/4885TSHR 4428/4885 |
| US-10870657-B2 | Compounds for the treatment of cancer and inflammatory disease | MAPK6, MAP3K6, MAPK4 | CETP 3121/4885LMNA 3509/4885TSHR 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.