Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 1/20 | 0.40 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169213 | 0.89 | CETP (0.47) | ARCETPMAPK1CYP3A4MAPT | |
| SCHEMBL8664260 | 0.83 | ALDH1A1 (0.45) | ARCYP3A4MAPTNR1H2NR1H3 | |
| SCHEMBL18700509 | 0.83 | LTB4R2 (0.48) | ARLTB4R2HDAC3HDAC1HDAC2 | |
| SCHEMBL5500471 | 0.83 | CYP3A4 (0.44) | CETPMAPK1CYP3A4MAPTLTB4R2 | |
| SCHEMBL23072505 | 0.82 | TAAR1 (0.46) | ARCETPMAPK1CYP3A4MAPT | |
| SCHEMBL8626864 | 0.82 | CYP3A4 (0.55) | CETPMAPK1CYP3A4MAPTALDH1A1 | |
| SCHEMBL6859772 | 0.81 | NR1H2 (0.38) | ARCYP3A4NR1H2NR1H3ALDH1A1 | |
| SCHEMBL28142156 | 0.81 | TLR8 (0.41) | CETPMAPK1LTB4R2HDAC3HDAC1 | |
| SCHEMBL7755356 | 0.80 | NR1H2 (0.54) | ARMAPK1CYP3A4MAPTNR1H2 | |
| SCHEMBL19265466 | 0.79 | HTR7 (0.43) | CETPMAPK1MAPTLTB4R2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846676-B1 | Process for the preparation of aromatic amines from aryl chlorides | AXIVA GMBH (DE) | 2001-02-07 | — | — | EP | disclosed |
| US-5831128-A | Synthesis of aromatic amines from chloroamatics | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| EP-0846676-A1 | Process for the preparation of aromatic amines from aryl chlorides | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-10 | — | — | EP | disclosed |