Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18454988 | 0.83 | NOTUM (0.46) | NOTUMMAPTHSP90AA1GAAKMT2A | |
| SCHEMBL19621353 | 0.80 | NOTUM (0.44) | NOTUMMAPTHSP90AA1GAAKMT2A | |
| SCHEMBL27575326 | 0.78 | KMO (0.43) | MAPTKMT2ATDP1OPRL1LMNA | |
| SCHEMBL26047235 | 0.74 | NPC1 (0.41) | NOTUMMAPTLMNASMN1; SMN2 | |
| SCHEMBL9399058 | 0.74 | CYP2C9 (0.49) | NOTUMMAPTKMT2AOPRL1LMNA | |
| SCHEMBL458343 | 0.73 | NOTUM (0.48) | NOTUMSIGMAR1 | |
| SCHEMBL18411525 | 0.72 | HSP90AA1 (0.44) | NOTUMMAPTHSP90AA1GAAKMT2A | |
| SCHEMBL22049055 | 0.72 | NOTUM (0.44) | NOTUMMAPTHSP90AA1GAAKMT2A | |
| SCHEMBL16959637 | 0.72 | NOTUM (0.41) | NOTUMOPRL1 | |
| SCHEMBL59138 | 0.72 | NOTUM (0.55) | NOTUMMAPTHSP90AA1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562233-B1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | JNC CORP (JP) | 2019-07-17 | — | — | EP | disclosed |