Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457755 | 0.77 | NPC1 (0.40) | PDK2PDK4NPC1RAB9AKDM1A | |
| SCHEMBL6882613 | 0.77 | ALOX5 (0.55) | HSD17B1HSD17B2NPC1RAB9AGABRA1 | |
| SCHEMBL457300 | 0.77 | KDM1A (0.49) | HTR2CKDM1A | |
| SCHEMBL9398855 | 0.75 | OPRL1 (0.47) | NOTUMRAB9A | |
| Hydrochloric Acid SCHEMBL6197567 | 0.74 | HTR2C (0.56) | NOTUMHTR2CGABRA1GABRB2 | |
| SCHEMBL10091179 | 0.74 | DGAT1 (0.37) | PDK2PDK4HSD17B1HSD17B2NPC1 | |
| SCHEMBL27537246 | 0.73 | SLC6A9 (0.46) | KDM1AKDM1B | |
| SCHEMBL22202819 | 0.73 | SIGMAR1 (0.36) | NOTUMHTR2CPDK2PDK4KCNA3 | |
| SCHEMBL21169701 | 0.73 | NOTUM (0.39) | NOTUMSIGMAR1 | |
| SCHEMBL6160494 | 0.73 | SLC6A2 (0.53) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |