Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119666 | 0.86 | GHSR (0.56) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2117478 | 0.84 | GHSR (0.50) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2119468 | 0.81 | ALDH1A1 (0.39) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2119638 | 0.78 | KDM4E (0.51) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2120109 | 0.77 | SLC40A1 (0.46) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2119636 | 0.77 | GHSR (0.52) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2120149 | 0.77 | TRIM24 (0.48) | GHSRKMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL2121413 | 0.77 | GHSR (0.50) | GHSRKMT2AALDH1A1KDM4EMEN1 | |
| SCHEMBL2117332 | 0.77 | KCNJ1 (0.44) | KMT2AMAPTCYP3A4PTGES2TP53 | |
| SCHEMBL2119380 | 0.76 | LMNA (0.39) | ALDH1A1MAPTHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
| EP-2382190-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | European Molecular Biology Laboratory (EMBL) (DE) | 2011-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1A, HIF1AN, EGLN3 | GHSR 1390/4885KMT2A 290/4885ALDH1A1 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.