Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 19/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16944572 | 0.85 | OPRK1 (0.63) | OPRK1 | |
| SCHEMBL18994656 | 0.82 | FLT3 (0.41) | OPRK1SSTR4 | |
| SCHEMBL20045330 | 0.77 | OPRK1 (0.46) | OPRK1 | |
| SCHEMBL3953284 | 0.76 | KDM4E (0.48) | — | |
| SCHEMBL2418069 | 0.76 | EPHX2 (0.56) | — | |
| SCHEMBL22907106 | 0.73 | OPRK1 (0.37) | OPRK1SSTR4 | |
| SCHEMBL29631786 | 0.72 | HSD11B1 (0.46) | OPRK1 | |
| SCHEMBL25768617 | 0.70 | CKS1B (0.50) | OPRK1SSTR4 | |
| SCHEMBL25316582 | 0.69 | PDE3B (0.38) | OPRK1SSTR4 | |
| SCHEMBL30507261 | 0.69 | PDE3B (0.38) | OPRK1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884978-B1 | NOVEL KAPPA OPIOID LIGANDS | SCRIPPS RESEARCH INST (US) | 2019-07-17 | — | — | EP | disclosed |