SCHEMBL2117196

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20601440	0.83	ALDH1A1 (0.43)	MAPTLMNAHTTALDH1A1MAPK1
	SCHEMBL1464772	0.82	CA12 (0.44)	MAPTLMNAHTTALDH1A1ALOX15
	SCHEMBL31430569	0.82	CA12 (0.44)	MAPTLMNAHTTALDH1A1ALOX15
	SCHEMBL15456848	0.81	ATM (0.44)	TDP1CYP3A4LMNACYP1A2CYP2C9
	SCHEMBL1465342	0.81	LMNA (0.50)	TDP1MAPTCYP3A4LMNAALDH1A1
	SCHEMBL4859733	0.81	LMNA (0.46)	TDP1MAPTCYP3A4LMNAHTT
	SCHEMBL14008570	0.81	ATM (0.44)	TDP1CYP3A4LMNACYP1A2CYP2C9
	SCHEMBL31759483	0.80	NOTUM (0.41)	LMNAHTTNOTUMKCNN4
	SCHEMBL2119103	0.79	NOTUM (0.40)	LMNAHTTKIF11NOTUMKCNN4
	SCHEMBL5673703	0.78	LMNA (0.49)	TDP1MAPTCYP3A4LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.