Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24486985 | 0.89 | MMP2 (0.43) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21172142 | 0.88 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21171899 | 0.85 | AKR1B10 (0.43) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21533672 | 0.84 | MAOB (0.48) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21171787 | 0.81 | MAOB (0.44) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24818334 | 0.81 | MEN1 (0.42) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21172140 | 0.81 | MAOB (0.44) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21171806 | 0.81 | KDM4E (0.49) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL21171797 | 0.80 | MMP2 (0.50) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24486795 | 0.79 | MMP2 (0.49) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11352325-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | WATERS TECHNOLOGIES CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-11353461-B2 | Methods of enhancing MS detection of tagged glycans | WATERS TECHNOLOGIES CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-11061023-B2 | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals | WATERS TECHNOLOGIES CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20190331669-A1 | FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS | WATERS TECHNOLOGIES CORPORATION (US) | 2019-10-31 | — | — | US | disclosed |
| US-20190219587-A1 | METHODS OF ENHANCING MS DETECTION OF TAGGED GLYCANS | WATERS TECHNOLOGIES CORPORATION | 2019-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11352325-B2 | Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals | FUT5, FUT6, ST3GAL3 | KDM4E 2975/4885HSD17B10 4361/4885ALDH1A1 1650/4885 |
| US-20190331669-A1 | FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES THROUGH REDUCTIVE AMINATION FOR ENHANCED MS SIGNALS | FUT5, FUT6, OGT | KDM4E 3466/4885HSD17B10 2541/4885ALDH1A1 264/4885 |
| US-11061023-B2 | Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals | FUT5, FUT6, OGT | KDM4E 3466/4885HSD17B10 2541/4885ALDH1A1 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.