Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | UBE2I | P63279 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2120046 | 0.87 | CYP2C9 (0.37) | CYP2C9CYP11B1CYP11B2KMT2AUBE2I | |
| SCHEMBL2117541 | 0.87 | ACSS2 (0.40) | CYP2C9POLBKDM4ELMNATRIM24 | |
| SCHEMBL2117311 | 0.78 | HSD17B1 (0.43) | CYP2C9KMT2AUBE2ISAE1UBA2 | |
| SCHEMBL2117866 | 0.78 | TAAR1 (0.47) | CYP2C9KMT2AUBE2ISAE1UBA2 | |
| SCHEMBL2118249 | 0.78 | PSEN1 (0.45) | CYP2C9KMT2AKDM4ELMNAMAPT | |
| SCHEMBL2119290 | 0.78 | TRIM24 (0.55) | CYP2C9POLBKDM4ELMNAMAPT | |
| SCHEMBL15921445 | 0.72 | KDM4E (0.43) | LRRK2KMT2APOLBKDM4ES1PR1 | |
| SCHEMBL2119068 | 0.69 | PIK3C3 (0.36) | CYP2C9CYP11B1CYP11B2KMT2APIK3C3 | |
| SCHEMBL2120206 | 0.68 | GAA (0.42) | CYP2C9KMT2ALMNATP53MAPT | |
| SCHEMBL2116901 | 0.67 | TRIM24 (0.49) | CYP2C9POLBMAPTTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1A, HIF1AN, EGLN3 | CYP2C9 2049/4885LRRK2 3323/4885CYP11B1 2444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.