Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | UBE2I | P63279 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118249 | 0.88 | PSEN1 (0.45) | CYP2C9C5AR1LMNAKDM4EKMT2A | |
| SCHEMBL2117866 | 0.88 | TAAR1 (0.47) | HSD17B1HSD17B2CYP2C9C5AR1TRIM24 | |
| SCHEMBL2117632 | 0.80 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2C9C5AR1NPC1 | |
| SCHEMBL2117541 | 0.79 | ACSS2 (0.40) | CYP2C9TRIM24LMNAKDM4E | |
| SCHEMBL2117226 | 0.78 | CYP2C9 (0.39) | CYP2C9TRIM24LMNAUBE2ISAE1 | |
| SCHEMBL2120046 | 0.77 | CYP2C9 (0.37) | CYP2C9NPC1RAB9ALMNAUBE2I | |
| SCHEMBL2118381 | 0.76 | HSD17B1 (0.43) | HSD17B1HSD17B2CYP2C9C5AR1NPC1 | |
| SCHEMBL2119838 | 0.75 | HSD17B1 (0.44) | HSD17B1HSD17B2CYP2C9C5AR1NPC1 | |
| SCHEMBL2119088 | 0.75 | TRIM24 (0.60) | TRIM24KMT2AMEN1SMN1; SMN2KAT6A | |
| SCHEMBL2117308 | 0.69 | MAPT (0.55) | C5AR1NPC1LMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | HSD17B1 3178/4885HSD17B2 3651/4885CYP2C9 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.