Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.37 |
| ▸ | UBE2I | P63279 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117311 | 0.88 | HSD17B1 (0.43) | LMNACYP2C9C5AR1KMT2AGAA | |
| SCHEMBL2118249 | 0.88 | PSEN1 (0.45) | LMNACYP2C9C5AR1PIK3CDKMT2A | |
| SCHEMBL2118388 | 0.80 | LMNA (0.41) | LMNACYP2C9C5AR1CYP2C8CYP2C18 | |
| SCHEMBL2117541 | 0.79 | ACSS2 (0.40) | LMNACYP2C9TRIM24KDM4EPOLB | |
| SCHEMBL2117226 | 0.78 | CYP2C9 (0.39) | LMNACYP2C9KMT2ATRIM24UBE2I | |
| SCHEMBL2118443 | 0.77 | LMNA (0.38) | LMNACYP2C9C5AR1CYP2C8CYP2C18 | |
| SCHEMBL2120046 | 0.77 | CYP2C9 (0.37) | LMNACYP2C9PIK3CDKMT2AUBE2I | |
| SCHEMBL2122135 | 0.76 | LMNA (0.41) | LMNACYP2C9C5AR1PIK3CDGAA | |
| SCHEMBL2120619 | 0.75 | TRIM24 (0.57) | TAAR1KMT2ATRIM24MEN1ALDH1A1 | |
| SCHEMBL2119431 | 0.75 | LMNA (0.41) | LMNACYP2C9C5AR1PIK3CDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | TAAR1 4100/4885LMNA 2529/4885CYP2C9 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.