Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 6/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5315829 | 0.82 | MMP2 (0.49) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8663329 | 0.79 | KDM4E (0.69) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13647562 | 0.76 | KDM4E (0.42) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL736223 | 0.71 | KDM4E (0.45) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL16921604 | 0.71 | KDM4E (0.59) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL8397201 | 0.67 | MMP2 (0.47) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| E637 SCHEMBL41817 | 0.67 | KDM4E (0.55) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| E637 SCHEMBL1870685 | 0.67 | KDM4E (0.55) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| E637 SCHEMBL23309786 | 0.65 | KDM4E (0.53) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| E637 SCHEMBL6657728 | 0.65 | KDM4E (0.53) | KDM4EPOLBALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310778-B1 | KOJIC ACID-DERIVED MANNICH BASES WITH BIOLOGICAL EFFECT | AYTEMIR MUTLU (TR) | 2019-07-17 | — | — | EP | disclosed |