Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.41 |
| ▸ | CCR2 | P41597 | 4/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119935 | 0.88 | PGR (0.39) | PGRHSD17B1HSD17B2NR3C1AR | |
| SCHEMBL2119814 | 0.84 | CCR2 (0.40) | PGRCCR2HSD17B1HSD17B2NR3C1 | |
| SCHEMBL29498140 | 0.82 | CYP2C9 (0.47) | HSD17B1HSD17B2POLBRAB9AMAPT | |
| SCHEMBL2120761 | 0.80 | HSD17B1 (0.43) | PGRHSD17B1HSD17B2NR3C1AR | |
| SCHEMBL2121470 | 0.78 | HSD17B1 (0.44) | PGRHSD17B1HSD17B2NR3C1AR | |
| SCHEMBL2119688 | 0.77 | PRF1 (0.47) | RAB9AMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL2119515 | 0.74 | CCR9 (0.40) | HSD17B1HSD17B2MAPTALDH1A1 | |
| SCHEMBL2118049 | 0.74 | ALDH1A1 (0.40) | HSD17B1HSD17B2RAB9AMAPTKDM4E | |
| SCHEMBL2117835 | 0.74 | MAPT (0.39) | PGRHSD17B1HSD17B2MAPTTP53 | |
| SCHEMBL2119262 | 0.74 | MAPT (0.37) | PGRHSD17B1HSD17B2RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
| EP-2382190-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | European Molecular Biology Laboratory (EMBL) (DE) | 2011-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1A, HIF1AN, EGLN3 | PGR 1586/4885CCR2 894/4885HSD17B1 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.