SCHEMBL21176322

SCHEMBL21176322

CC(C)(C)OC(=O)N1CC(NC(=O)C(=O)[C@H]2CCC(=O)N2Cc2ccccc2)C1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 1/20 0.44
USP30 Q70CQ3 3/20 0.44
KMT2A Q03164 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
P2RX7 Q99572 3/20 0.42
GAA P10253 1/20 0.42
STS P08842 1/20 0.42
CAPN1 P07384 2/20 0.41
BRD4 O60885 1/20 0.41
JAK2 O60674 1/20 0.40
JAK1 P23458 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21176233 0.91 GPR119 (0.50) GPR119USP30KMT2AL3MBTL1STS
SCHEMBL19975374 0.87 P2RX7 (0.47) KMT2AP2RX7GAACAPN1
SCHEMBL21176249 0.84 P2RX7 (0.46) KMT2AP2RX7GAACAPN1
SCHEMBL21183582 0.83 P2RX7 (0.51) KMT2AP2RX7GAACAPN1
SCHEMBL21183578 0.83 P2RX7 (0.51) KMT2AP2RX7GAACAPN1
SCHEMBL21176193 0.82 ALDH1A1 (0.43) KMT2AP2RX7GAACAPN1
SCHEMBL21176300 0.82 P2RX7 (0.43) KMT2AP2RX7GAACAPN1
SCHEMBL21176360 0.82 KMT2A (0.45) KMT2AL3MBTL1P2RX7GAACAPN1
SCHEMBL19974874 0.82 P2RX7 (0.43) KMT2AP2RX7GAACAPN1
SCHEMBL21183549 0.81 EPHX2 (0.50) KMT2AL3MBTL1P2RX7GAACAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C GPR119 263/4885USP30 2721/4885KMT2A 4031/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C GPR119 448/4885USP30 3098/4885KMT2A 4177/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C GPR119 263/4885USP30 2721/4885KMT2A 4031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.