SCHEMBL21176349

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19975126	0.89	ALDH1A1 (0.47)	ALDH1A1GAAL3MBTL1F2ADAM17
	SCHEMBL19975279	0.84	MAPT (0.56)	ALDH1A1GAAL3MBTL1F2EPHX2
	SCHEMBL7352008	0.81	METAP2 (0.70)	ALDH1A1GAAL3MBTL1F2MAPT
	Hydrochloric Acid SCHEMBL7505505	0.80	METAP2 (0.69)	ALDH1A1GAAL3MBTL1F2MAPT
	Hydrochloric Acid SCHEMBL7354304	0.80	METAP2 (0.69)	ALDH1A1GAAL3MBTL1F2MAPT
	SCHEMBL19974746	0.80	MASP2 (0.57)	ADAM17MASP2KMT2ARXFP1
	SCHEMBL19975129	0.80	MASP2 (0.51)	ALDH1A1ADAM17MASP2KMT2ARXFP1
	SCHEMBL19975237	0.80	MASP2 (0.53)	ALDH1A1ADAM17MASP2KMT2ARXFP1
	SCHEMBL19975379	0.80	ALDH1A1 (0.51)	ALDH1A1GAAL3MBTL1F2EPHX2
	SCHEMBL19975335	0.79	ALDH1A1 (0.48)	ALDH1A1GAAL3MBTL1F2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.