Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177781 | 0.89 | KLKB1 (0.36) | S1PR1S1PR3KLKB1MAOBALDH1A1 | |
| SCHEMBL21177310 | 0.86 | KLKB1 (0.32) | KLKB1 | |
| SCHEMBL21179387 | 0.84 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL19780407 | 0.81 | KLKB1 (0.42) | S1PR1S1PR3KLKB1 | |
| SCHEMBL21177362 | 0.79 | KLKB1 (0.38) | KLKB1ALDH1A1 | |
| SCHEMBL21177318 | 0.79 | KLKB1 (0.33) | KLKB1 | |
| SCHEMBL21177161 | 0.78 | KLKB1 (0.42) | KLKB1ALDH1A1 | |
| SCHEMBL21190192 | 0.75 | ALOX15 (0.37) | S1PR1S1PR3KLKB1ALDH1A1ALOX5 | |
| SCHEMBL21190089 | 0.75 | KLKB1 (0.44) | S1PR1S1PR3KLKB1ALDH1A1MAPT | |
| SCHEMBL21177142 | 0.75 | KLKB1 (0.36) | S1PR1S1PR3KLKB1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |
| WO-2019142053-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-07-25 | — | — | WO | disclosed |