Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21184102 | 0.90 | LMNA (0.44) | LMNACYP2C9RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL27299791 | 0.73 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL2044334 | 0.70 | PKM (0.46) | PKML3MBTL1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL21177572 | 0.70 | SMN1; SMN2 (0.42) | LMNACYP2C9RAB9AALDH1A1KMT2A | |
| SCHEMBL13590567 | 0.68 | CYP2C9 (0.49) | LMNACYP2C9RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL963660 | 0.68 | CYP2C9 (0.49) | LMNACYP2C9RAB9AL3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL7814309 | 0.68 | PKM (0.49) | PKML3MBTL1KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL963659 | 0.68 | CYP2C9 (0.49) | LMNACYP2C9RAB9AL3MBTL1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL28163815 | 0.68 | PKM (0.48) | PKML3MBTL1 | |
| SCHEMBL31160508 | 0.67 | CHRNB2 (0.41) | L3MBTL1ALDH1A1KDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754861-A | Substituted alkynylene compounds as anticancer agents | 奥里吉恩肿瘤学有限公司 | 2024-10-11 | — | — | CN | disclosed |
| EP-3740473-A1 | SUBSTITUTED ALKYNYLENE COMPOUNDS AS ANTICANCER AGENTS | Aurigene Discovery Technologies Limited (IN) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019142126-A1 | SUBSTITUTED ALKYNYLENE COMPOUNDS AS ANTICANCER AGENTS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2019-07-25 | — | — | WO | disclosed |