Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119724 | 0.88 | TERT (0.51) | KAT6AMEN1KMT2AGHSRALDH1A1 | |
| SCHEMBL2118406 | 0.88 | ALDH1A1 (0.51) | KAT6AMEN1KMT2AGHSRALDH1A1 | |
| SCHEMBL2118542 | 0.80 | MEN1 (0.52) | MEN1KMT2AGHSRALDH1A1GAA | |
| SCHEMBL2118397 | 0.78 | ALDH1A1 (0.45) | MEN1KMT2AGHSRALDH1A1GAA | |
| SCHEMBL597553 | 0.72 | HTT (0.56) | KAT6AKMT2AALDH1A1GAAMAPT | |
| SCHEMBL2118662 | 0.70 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1GAAGFER | |
| SCHEMBL2119832 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1GAAGFER | |
| SCHEMBL2117978 | 0.70 | MAPT (0.45) | ALDH1A1GAAGFERCYP2C9MAPT | |
| SCHEMBL2120070 | 0.69 | MAPT (0.54) | KAT6AALDH1A1GAAMAPTLMNA | |
| SCHEMBL2118702 | 0.69 | MAPT (0.49) | MEN1KMT2AGHSRALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | KAT6A 2893/4885MEN1 3114/4885KMT2A 276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.