Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177752 | 0.73 | TSHR (0.40) | TSHR | |
| SCHEMBL21180339 | 0.73 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL21177501 | 0.70 | ALDH1A1 (0.39) | — | |
| SCHEMBL22614864 | 0.65 | NAAA (0.46) | TSHR | |
| SCHEMBL21179455 | 0.65 | ALDH1A1 (0.45) | TSHR | |
| SCHEMBL21177553 | 0.63 | NAAA (0.48) | TSHR | |
| SCHEMBL21177537 | 0.63 | NAAA (0.48) | TSHR | |
| SCHEMBL21177520 | 0.63 | NAAA (0.48) | TSHR | |
| SCHEMBL6709810 | 0.62 | — | — | |
| SCHEMBL707000 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2978768-B1 | CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2017-11-29 | — | — | EP | claimed |
| EP-1341843-B2 | MINERAL-FILLED ELASTOMER COMPOSITIONS | MOMENTIVE PERFORMANCE MAT INC (US) | 2016-03-23 | — | — | EP | claimed |
| EP-1560836-B1 | PROCESS FOR MANUFACTURE OF BLOCKED MERCAPTOSILANE COUPLING AGENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-30 | — | — | EP | claimed |
| EP-1669401-B1 | Tire with tread containing combination of specialized elastomer and coupling agent | GOODYEAR TIRE & RUBBER (US) | 2013-07-31 | — | — | EP | claimed |
| EP-1869057-B1 | AQUEOUS CATALYTIC PROCESS FOR THE PREPARATION OF THIOCARBOXYLATE SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2012-12-19 | — | — | EP | claimed |
| EP-1491545-B1 | Method of preparing a composite of hydrophobated amorphous silica employing blocked mercaptoalkoxysilanes | GOODYEAR TIRE & RUBBER (US) | 2009-01-14 | — | — | EP | claimed |
| EP-0958298-B2 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-10-22 | — | — | EP | claimed |
| EP-1341843-B1 | MINERAL-FILLED ELASTOMER COMPOSITIONS | GEN ELECTRIC (US) | 2007-01-17 | — | — | EP | claimed |
| EP-0958298-B1 | BLOCKED MERCAPTOSILANE COUPLING AGENTS FOR FILLED RUBBERS | CROMPTON CORP (US) | 2003-05-07 | — | — | EP | claimed |
| US-20260132274-A1 | TIRE COMPONENT FROM RUBBER COMPOSITION INCLUDING GUAYULE RUBBER AND EUTECTIC COMPOSITION AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2026-05-14 | — | — | US | disclosed |
| US-20260071068-A1 | RESIN-EXTENDED RUBBER AND PROCESS FOR PREPARING | BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) | 2026-03-12 | — | — | US | disclosed |
| EP-4055098-B1 | TIRE HAVING TREAD OF SPECIFIED RUBBER COMPOSITION AND RELATED METHODS | BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-12466214-B2 | Tire tread rubber composition | BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) | 2025-11-11 | — | — | US | disclosed |
| US-20250320350-A1 | RUBBER FORMULATIONS YIELDING IMPROVED DYNAMIC PROPERTIES AND WEAR | BRIDGESTONE CORP (JP) | 2025-10-16 | — | — | US | disclosed |
| US-7256231-B2 | Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes | BRIDGESTONE CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| US-20060106143-A1 | Silica-reinforced rubber compounded with blocked mercaptosilanes and alkyl alkoxysilanes | BRIDGESTONE CORPORATION | 2006-05-18 | — | — | US | disclosed |
| EP-1609516-A1 | Process and device for extracting substances from silan-modified fillers | Degussa AG (DE) | 2005-12-28 | — | — | EP | disclosed |
| EP-1256604-B1 | Biopolymers, biooligomers, oxidic or silicate Filler modified by silanes, method for its production and use | DEGUSSA (DE) | 2005-08-31 | — | — | EP | disclosed |
| EP-1357156-A2 | Silane modified oxidic or silicate filler, method for its manufacture and its use | Degussa AG (DE) | 2003-10-29 | — | — | EP | disclosed |
| EP-1256604-A2 | Biopolymers, biooligomers, oxidic or silicate Filler modified by silanes, method for its production and use | Degussa AG (DE) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260132274-A1 | TIRE COMPONENT FROM RUBBER COMPOSITION INCLUDING GUAYULE RUBBER AND EUTECTIC COMPOSITION AND RELATED METHODS | GEMIN5, GMNN, TAF5 | TSHR 3114/4885 |
| US-20260071068-A1 | RESIN-EXTENDED RUBBER AND PROCESS FOR PREPARING | RER1, SMCHD1, REL | TSHR 3188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.