Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119629 | 0.86 | GHSR (0.43) | GHSRSCN9AP2RX7ALDH1A1MAPT | |
| SCHEMBL2119284 | 0.85 | TRIM24 (0.45) | GHSRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2119861 | 0.84 | EDNRA (0.39) | GHSRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL2119299 | 0.82 | P2RX7 (0.43) | GHSRSCN9AP2RX7KDM4EALDH1A1 | |
| SCHEMBL2116789 | 0.80 | GHSR (0.53) | GHSRP2RX7ALDH1A1MAPTRAB9A | |
| SCHEMBL2121515 | 0.80 | GHSR (0.43) | GHSRSCN9AP2RX7MAPTBRD4 | |
| SCHEMBL2121465 | 0.80 | SCN9A (0.46) | GHSRSCN9AP2RX7KDM4EALDH1A1 | |
| SCHEMBL2117745 | 0.80 | ALDH1A1 (0.39) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2121942 | 0.79 | SLC40A1 (0.46) | GHSRP2RX7KDM4EALDH1A1MAPT | |
| SCHEMBL2119214 | 0.79 | SLC40A1 (0.46) | GHSRP2RX7KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1A, HIF1AN, EGLN3 | GHSR 1390/4885SCN9A 3268/4885P2RX7 1426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.