Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | PPARA | Q07869 | 6/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | CPA3 | P15088 | 3/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | CPB1 | P15086 | 1/20 | 0.44 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193057 | 1.00 | PPARG (0.50) | PPARGPPARAMDM2CYP1A2ALPI | |
| SCHEMBL22033162 | 0.90 | SLC7A5 (0.47) | PPARGPPARAMDM2CYP1A2ALPI | |
| SCHEMBL22033163 | 0.90 | SLC7A5 (0.47) | PPARGPPARAMDM2CYP1A2ALPI | |
| SCHEMBL29254130 | 0.89 | PPARG (0.49) | PPARGPPARA | |
| SCHEMBL12583014 | 0.86 | MDM2 (0.47) | PPARGPPARAMDM2CYP1A2ALPI | |
| SCHEMBL27125750 | 0.86 | GRIA2 (0.46) | PPARGPPARAFOLH1 | |
| SCHEMBL26985751 | 0.86 | GRIA2 (0.46) | PPARGPPARAFOLH1 | |
| SCHEMBL26985913 | 0.86 | GRIA2 (0.46) | PPARGPPARAFOLH1 | |
| SCHEMBL30703204 | 0.85 | SLC1A1 (0.51) | PPARGPPARAMDM2CYP1A2SLC1A1 | |
| SCHEMBL4367203 | 0.85 | PPARG (0.52) | PPARGPPARAMDM2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| US-20120095218-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | NAGASE & CO., LTD. (JP) | 2012-04-19 | — | — | US | disclosed |
| US-6639094-B2 | Process for producing α-aminoketone derivatives | AJINOMOTO CO., INC. (JP) | 2003-10-28 | — | — | US | disclosed |
| US-20020026081-A1 | Process for producing alpha-aminoketone derivatives | AJINOMOTO CO., INC. (JP) | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020026081-A1 | Process for producing alpha-aminoketone derivatives | AADAT, BCKDK, BCAT1 | PPARG 1688/4885PPARA 1366/4885MDM2 1885/4885 |
| US-20120095218-A1 | OPTICALLY ACTIVE QUATERNARY AMMONIUM SALT HAVING AXIAL ASYMMETRY, AND METHOD FOR PRODUCING ALPHA-AMINO ACID AND DERIVATIVE THEREOF BY USING THE SAME | AADAT, BCAT1, BCAT2 | PPARG 4567/4885PPARA 2633/4885MDM2 2574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.