Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809843 | 0.86 | AKR1C3 (0.48) | ALOX5PTGS1LMNARAB9ANPC1 | |
| SCHEMBL809846 | 0.86 | TRPA1 (0.41) | ALOX5PTGS1LMNARAB9ANPC1 | |
| SCHEMBL726364 | 0.76 | JUN (0.55) | ALOX5PTGS1RAB9AKDM4EJUN | |
| SCHEMBL31518926 | 0.76 | JUN (0.55) | ALOX5PTGS1RAB9AKDM4EJUN | |
| SCHEMBL1088564 | 0.75 | JUN (0.44) | ALOX5PTGS1LMNARAB9AKDM4E | |
| SCHEMBL22599667 | 0.74 | AKR1C3 (0.48) | ALOX5PTGS1LMNARAB9ANPC1 | |
| SCHEMBL809905 | 0.74 | HTR2C (0.39) | PTGS1LMNARAB9ANPC1PKM | |
| SCHEMBL28078757 | 0.73 | AKR1C3 (0.47) | ALOX5PTGS1LMNARAB9ANPC1 | |
| SCHEMBL3906645 | 0.73 | AKR1C3 (0.53) | ALOX5PTGS1LMNARAB9AKDM4E | |
| SCHEMBL29030377 | 0.73 | TRPA1 (0.50) | ALOX5PTGS1LMNARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358641-B2 | Monoliths with attached recognition compounds, arrays thereof and uses thereof | DICE MOLECULES SV, LLC (US) | 2019-07-23 | — | — | US | disclosed |