Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | VCP | P55072 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809843 | 0.84 | AKR1C3 (0.48) | AKR1C3AKR1C2ALOX5PTGS1JUN | |
| SCHEMBL22599667 | 0.84 | AKR1C3 (0.48) | AKR1C3AKR1C2ALOX5PTGS1JUN | |
| SCHEMBL3906645 | 0.82 | AKR1C3 (0.53) | AKR1C3AKR1C2ALOX5PTGS1JUN | |
| SCHEMBL29254247 | 0.81 | HSD17B1 (0.39) | KDM4ELMNAMEN1TTRTP53 | |
| SCHEMBL4842042 | 0.80 | CYP3A4 (0.47) | AKR1C3AKR1C2KDM4ECYP3A4ALDH1A1 | |
| SCHEMBL726364 | 0.79 | JUN (0.55) | ALOX5PTGS1JUNNFKB1KDM4E | |
| SCHEMBL31518926 | 0.79 | JUN (0.55) | ALOX5PTGS1JUNNFKB1KDM4E | |
| SCHEMBL11308643 | 0.77 | CFD (0.58) | AKR1C3AKR1C2ALOX5PTGS1KDM4E | |
| SCHEMBL3987965 | 0.77 | CFD (0.46) | AKR1C3AKR1C2PTGS1KDM4EMEN1 | |
| SCHEMBL11110793 | 0.77 | ALDH1A1 (0.52) | KDM4EMEN1TP53MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278910-A | Preparation method of levalbuterol | 浙江工业大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-105753721-A | Synthesis method of levalbuterol | 浙江工业大学 | 2016-07-13 | — | — | CN | disclosed |