Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23023052 | 0.88 | HIF1A (0.47) | ALDH1A1KMT2ALMNATSHRKDM4E | |
| Hydrochloric Acid SCHEMBL23004994 | 0.87 | HIF1A (0.46) | ALDH1A1KMT2ALMNATSHRKDM4E | |
| SCHEMBL31126904 | 0.84 | KMT2A (0.53) | ALDH1A1KMT2AHIF1AMEN1TP53 | |
| SCHEMBL9938759 | 0.83 | TP53 (0.49) | ALDH1A1KMT2AMEN1TP53CYP3A4 | |
| SCHEMBL30096080 | 0.82 | HDAC6 (0.58) | ALDH1A1KMT2AMEN1TP53CYP3A4 | |
| SCHEMBL21180879 | 0.80 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNATSHRKDM4E | |
| SCHEMBL2734356 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KMT2ALMNATSHRKDM4E | |
| SCHEMBL20535307 | 0.74 | HDAC6 (0.68) | ALDH1A1KMT2ALMNAHPGDMEN1 | |
| SCHEMBL3861586 | 0.74 | CYP2D6 (0.60) | KMT2ATSHRKDM4EHIF1AHSD17B10 | |
| SCHEMBL417711 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115869428-A | HDAC6 inhibitors and imaging agents | 通用医疗公司 | 2023-03-31 | — | — | CN | disclosed |
| CN-110770206-B | HDAC6 inhibitors | 通用医疗公司 | 2022-11-25 | — | — | CN | disclosed |