Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2366337 | 0.80 | ADRB1 (0.47) | ADRB1GPR119MEN1KMT2AMAPT | |
| SCHEMBL21180901 | 0.77 | CYP3A4 (0.52) | GPR119AKR1C3 | |
| SCHEMBL22537505 | 0.76 | ADRB1 (0.55) | ADRB1GPR119MEN1KMT2AMAPT | |
| SCHEMBL15189519 | 0.76 | GPR119 (0.58) | ADRB1GPR119MEN1KMT2AMAPT | |
| SCHEMBL10142446 | 0.76 | USP2 (0.59) | ADRB1GPR119MEN1KMT2AMAPT | |
| SCHEMBL20133771 | 0.75 | ADRB1 (0.49) | ADRB1GPR119MEN1KMT2AMAPT | |
| SCHEMBL10063748 | 0.75 | ADRB1 (0.70) | ADRB1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL3414344 | 0.75 | ADRB1 (0.70) | ADRB1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL7105773 | 0.75 | ADRB1 (0.70) | ADRB1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL169776 | 0.75 | ADRB1 (0.53) | ADRB1GPR119MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221304-B1 | NOVEL CARBOXYLIC ACID COMPOUNDS USEFUL FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 | LILLY CO ELI (US) | 2019-07-24 | — | — | EP | disclosed |