Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.44 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118767 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL170993 | 0.78 | LMNA (0.56) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL6437449 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL9067683 | 0.76 | LMNA (0.54) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL2118813 | 0.76 | LMNA (0.53) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL139079 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL1856364 | 0.74 | LMNA (0.51) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL9067475 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| Phosphocholine SCHEMBL10948480 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL15312730 | 0.73 | ADRA1A (0.58) | SMN1; SMN2ADRA1ALMNAESR1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-4121801-B1 | INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX | ALCON INC (CH) | 2024-04-17 | — | — | EP | claimed |
| EP-4146461-B1 | METHOD FOR PRODUCING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-03-13 | — | — | EP | claimed |
| EP-3774310-B1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2022-07-06 | — | — | EP | claimed |
| EP-3746820-B1 | CONTACT LENSES WITH A LUBRICIOUS COATING THEREON | ALCON INC (CH) | 2022-02-16 | — | — | EP | claimed |
| US-20140288259-A1 | SURFACE-MODIFIED ULTRAVIOLET BLOCKING POWDER AND ULTRAVIOLET BLOCKING COMPOSITION INCLUDING SAME | KCI CO., LTD. (KR) | 2014-09-25 | — | — | US | claimed |
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | claimed |
| US-5461433-A | Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups | NOF CORPORATION (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0537972-A1 | Treating solution for contact lenses | NOF CORPORATION (JP) | 1993-04-21 | — | — | EP | claimed |
| US-11029446-B2 | Method for producing MPS-compatible water gradient contact lenses | ALCON INC. (CH) | 2021-06-08 | — | — | US | disclosed |
| US-20190176415-A1 | METHOD FOR PRODUCING MPS-COMPATIBLE WATER GRADIENT CONTACT LENSES | ALCON INC. (CH) | 2019-06-13 | — | — | US | disclosed |
| US-20140288259-A1 | SURFACE-MODIFIED ULTRAVIOLET BLOCKING POWDER AND ULTRAVIOLET BLOCKING COMPOSITION INCLUDING SAME | KCI CO., LTD. (KR) | 2014-09-25 | — | — | US | disclosed |
| EP-2772247-A1 | SURFACE-MODIFIED ULTRAVIOLET BLOCKING POWDER AND ULTRAVIOLET BLOCKING COMPOSITION INCLUDING SAME | KCI Co.,ltd (KR) | 2014-09-03 | — | — | EP | disclosed |
| EP-2660252-A2 | POLYSACCHARIDE-BASED GRAFT COPOLYMER AND COMPOSITION COMPRISING SAME FOR PERSONAL CARE | Kci Limited (KR) | 2013-11-06 | — | — | EP | disclosed |
| US-8318824-B2 | Hydrophilic polyolefin sintered body | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120095121-A1 | HYDROPHILIC POLYOLEFIN SINTERED BODY | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2174975-A1 | HYDROPHILIC POLYOLEFIN SINTERED BODY | Asahi Kasei Chemicals Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-0537972-B1 | Treating solution for contact lenses | NOF CORP (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5461433-A | Cleaning contact lens by immersing in solution containing copolymer where one of the monomers contains phsophate and tertiary ammonium groups | NOF CORPORATION (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0537972-A1 | Treating solution for contact lenses | NOF CORPORATION (JP) | 1993-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140288259-A1 | SURFACE-MODIFIED ULTRAVIOLET BLOCKING POWDER AND ULTRAVIOLET BLOCKING COMPOSITION INCLUDING SAME | C1QBP, PCTP, CD59 | SMN1; SMN2 4469/4885ADRA1A 1776/4885LMNA 1745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.