Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14754868 | 1.00 | CHRNB2 (0.35) | CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL14752138 | 0.82 | PIK3CD (0.31) | — | |
| SCHEMBL19156661 | 0.82 | PIK3CD (0.31) | — | |
| SCHEMBL19000154 | 0.76 | SLC6A9 (0.40) | CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL17010751 | 0.72 | MAOB (0.41) | CHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL14754875 | 0.71 | MEN1 (0.32) | SMN1; SMN2 | |
| SCHEMBL19617146 | 0.71 | MEN1 (0.37) | SMN1; SMN2 | |
| SCHEMBL19135574 | 0.70 | BCHE (0.35) | — | |
| SCHEMBL15615636 | 0.69 | MAPT (0.47) | SMN1; SMN2 | |
| SCHEMBL12206867 | 0.69 | PDK1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3513793-B1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2021-03-10 | — | — | EP | disclosed |
| EP-3513793-A1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | Incyte Holdings Corporation (US) | 2019-07-24 | — | — | EP | disclosed |