Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24772321 | 0.87 | LMNA (0.38) | GAAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL27042897 | 0.76 | LMNA (0.34) | ALDH1A1LMNAGABRA1GABRB2 | |
| SCHEMBL7076612 | 0.75 | TYR (0.33) | TYREGFR | |
| SCHEMBL952521 | 0.74 | GAA (0.41) | GAATDP1L3MBTL1KDM4EGABRA1 | |
| SCHEMBL17376732 | 0.74 | ERN1 (0.42) | TYRGAAL3MBTL1MAPK1LMNA | |
| SCHEMBL955871 | 0.73 | GAA (0.42) | GAATDP1L3MBTL1KDM4E | |
| SCHEMBL27260823 | 0.73 | ALOX5 (0.51) | TYRTDP1MEN1KMT2A | |
| SCHEMBL9520453 | 0.70 | CTRC (0.37) | TYRGAATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL3869269 | 0.70 | GABRA1 (0.36) | GAAL3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL3970026 | 0.69 | MAPK1 (0.53) | TYRGAAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019144041-A1 | DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |